WU Jie

WU Jie

WU Jie

Senior Principal Investigator

chmjie@nus.edu.sg
Education
2002-2006 Department of Chemistry, Beijing Normal University,B.S.
2006-2012 Department of Chemistry, Boston University,Ph.D.


Work Experience
2012-2015 Department of Chemistry and Chemical Engineering, Massachusetts Institute of Technology,Post-doctoral
2015-2015 Snapdragon Chemistry, Inc. Boston, Senior research scientist
2015-2021 Department of Chemistry, National University of Singapore,Assistant Professor
2021-Present Department of Chemistry, National University of Singapore,Associate Professor


Research Interests
1. Continuous-flow Synthesis
2. Photochemistry
3. Automated Synthesis

Honor & Award
2017-2019 Asian Core Program Lectureship Award (Korea, Thailand, China)
2018 NUS Chemistry Department Young Chemist Award
2019 Thieme Chemistry Journal Award
2020 The Distinguished Lectureship Award, The CSJ Asian International Symposium, The Chemical Society of Japan


Representative Publications

[1] Cai, B.; Cheo, H. W.; Liu, T.; Wu, J.* “Light-promoted Carbon-Carbon Bond Formation Utilizing Natural Gases as Feedstocks” Angew. Chem. Int. Ed. 2020, accepted. DOI: 10.1002/anie.202010710
[2] Wang, H.; Toh, R. W.; Shi, X.; Wang, T.; Cong, X.; Wu, J.* “Photo-mediated Selective Deconstructive Geminal Dihalogenation of Trisubstituted Alkenes” Nat. Commun. 2020, 11, 4462
[3] Kuang, Y.; Cao, H.; Tang, H.; Chew, J.; Chen, W.; Shi, X.; Wu, J.* “Visible Light Driven Deuteration of Formyl C-H and Hydridic C(sp3)-H Bonds in Feedstock Chemicals and Pharmaceutical Molecules” Chem. Sci. 2020, 11, 8912-8918
[4] Yan, J.; Cheo, H. W.; Teo, W. K.; Shi, X.; Wu, H.; Idres, S. B.; Deng. L.-W.; Wu, J.* “A Radical Smiles Rearrangement Promoted by Neutral Eosin Y as a Direct Hydrogen Atom Transfer Photocatalyst” J. Am. Chem. Soc. 2020, 142, 11357-11362 (Highlighted by Rational Science and X-MOL)
[5] Zhang, Y.; Yang, X.; Wu, J.*; Huang, D.* “Aerobic C-H Functionalization Using Pyrenedione as the Photocatalyst” Synthesis 2020, DOI: 10.1055/s-0040-1707135
[6] Zheng, L.; Xue, H.; Wong, W. K.; Cao, H.; Wu, J.*; Khan, A. S.* “Cloud-inspired Multiple Scattering for Light Intensified Photochemical Flow Reactors” React. Chem. Eng. 2020, 5, 1058-1063
[7] Jia, P.; Li, Q.; Poh, W. C.; Jiang, H.; Liu, H.; Deng, H.; Wu, J.* “Light-Promoted Bromine Radicl-Mediated Selective Alkylation and Amination of Unactivated C(sp3)-H Bonds” Chem 2020, 6, 1766-1776
[8] Cao, H.; Kuang, Y.; Shi, X.; Wong, K. L.; Tang, B. B.; Kwan, J. M. C.; Liu, X.; Wu, J.* “Photoinduced Site-Selective Alkenylation of Alkanes and Aldehydes with Aryl Alkenes” Nat. Commun. 2020, 11, 1956 (Highlighted by Synfacts 2020, 16, 0795 and chosen as Synfacts of the month. It has been higlighted by iCat, Phys. Org, Organic Chemistry Portal, and National University of Singapore (Suzhou) Research Institute)
[9] Xu, W.; Jiang, H.; Leng, J.; Ong, H.-W.; Wu, J.* “Visible-Light-Induced Selective Defluoroborylation of Polyfluoroarenes, gem-Difluoroalkenes, and Trifluoromethylalkenes” Angew. Chem. Int. Ed. 2020, 59, 4009-4016 (Highlighted by Rational Science and X-MOL)
[10] Zhang, Y.; Yang, X.; Tang, H.; Liang, D.; Wu, J.*, Huang, D.* “Pyrenediones as Versatile Photocatalysts for Oxygenation Reactions with in situ Generation of Hydrogen Peroxide under Visible Light” Green Chem. 2020, 22, 22-27


Patents
1. Wu, J.; Khan, A. S.; Liu, C.; Wu, W.; Chen, W.; Wang, M.; Xie, J. “Method and System for Synthesising Compounds” US Provisional Patent Application No. 62/925,031.
2. Wu, J.; Li, J.; Xue, C.; Mohamed D. “Lotus-Type Reactor for Large-Scale Continuous-Flow and Stop-Flow Synthesis” Application No. 10201700300X.
3. Wu, J.; Deng H.; Xue, F.; Mohamed, D. “Modular ‘Stop-Flow’ Parallel Microtubing Reactor Platform Useful for High-Pressure Reaction Screening” US 62/320726.


NUS Webpage

https://chemistry.nus.edu.sg/people/wu-jie/


Other Investigators

CHEN Jingsheng
CHEN Jingsheng

Chief Principal Investigator

msecj@nus.edu.sg
GONG Xiao
GONG Xiao

Senior Principal Investigator

elegong@nus.edu.sg
HU Jiangyong
HU Jiangyong

Chief Principal Investigator

ceehujy@nus.edu.sg
LIANG Yung Chii
LIANG Yung Chii

Senior Principal Investigator

chii@nus.edu.sg
LU Jiong
LU Jiong

Senior Principal Investigator

chmluj@nus.edu.sg
LU Yixin
LU Yixin

Chief Principal Investigator

chmlyx@nus.edu.sg
OUYANG Jianyong
OUYANG Jianyong

Senior Principal Investigator

mseoj@nus.edu.sg
WANG Qing
WANG Qing

Chief Principal Investigator

qing.wang@nus.edu.sg
XU Guo Qin
XU Guo Qin

Chief Principal Investigator

guoqin.xu@nusri.cn
XU Qinghua
XU Qinghua

Senior Principal Investigator

chmxqh@nus.edu.sg
YAN Wentao
YAN Wentao

Principal Investigator

mpeyanw@nus.edu.sg
ZENG Kaiyang
ZENG Kaiyang

Senior Principal Investigator

mpezk@nus.edu.sg