Education
1987-1991 B.Sc. in Chemistry, Fudan University, Shanghai, P.R. China
1995-2000 Ph.D. in Organic Chemistry, McGill University, Montreal, Canada
Work Experience
2003-2010 Assistant Professor, Department of Chemistry, National University of Singapore
2010-2014 Associate Professor, Department of Chemistry, National University of Singapore
2014-Present Professor, Department of Chemistry, National University of Singapore
2016-Present Principal Investigator, NUS Research Institute in Suzhou
Appointments
2017-2021 Vice-Dean, Faculty of Science, National University of Singapore
2021-Present Head, Department of Chemistry, National University of Singapore
Research Interests
Asymmetric catalysis and synthesis
Green and Sustainable Chemistry
Medicinal Chemistry
Publications
[1] Zheng, W.; Tan, B. B.; Ge, S.; Lu, Y. “Enantioselective Copper-Catalyzed Ring-Opening Diboration of Arylidene-cyclopropanes to Access Chiral Skipped 1,4- and 1,3-Diboronates”, J. Am. Chem. Soc. 2024, 146, 5366.
[2] Zhou, X.; Huang, Q.; Guo, J.; Dai, L.; Lu, Y. “Enantioselective De Novo Synthesis of ɑ,ɑ-Diarylketones from Alkynes”, Angew. Chem. Int. Ed. 2023, 62, e202310078.
[3] Zhou, X.; Huang, Q.; Guo, J.; Dai, L.; Lu, Y. “Molecular Editing of Pyrroles via a Skeletal Recasting Strategy”, ACS Cent. Sci. 2023, 9, 1758.
[4] Dai L.; Zhou, X.; Guo, J.; Dai, X.; Huang, Q.; Lu, Y. “Diastereo- and Atroposelective Synthesis of N-Arylpyrroles Enabled by Light-Induced Phosphoric Acid Catalysis”, Nat. Commun. 2023, 14, 4813.
[5] Wu, Z.; Wu, M.; Zhu, K.; Wu, J.; Lu, Y. “Photocatalytic Coupling of Electron-Deficient Alkenes using Oxalic Acid as a Traceless Linchpin”, Chem 2023, 9, 978.
[6] Tan, C. X. A.; Li, R.; Zhang, F.; Dai, L.; Ullah, N.; Lu, Y. “Synthesis of Axially Chiral CF3-Substituted 2-Arylpyrroles by Sequential Phosphine-Catalyzed Asymmetric [3+2] Annulation and Oxidative Central-to-Axial Chirality Transfer”, Angew. Chem. Int. Ed. 2022, 61, e202209494.
[7] Huang, Q.; Chen, Y.; Zhou, X.; Dai, L.; Lu, Y. “Nickel-Hydride-Catalyzed Diastereo- and Enantioselective Hydroalkylation of Cyclopropenes”, Angew. Chem. Int. Ed. 2022, 61, e202210560.
[8] Mei, G.-J.; Koay, W. L.; Guan, C. Y.; Lu, Y. “Atropisomers Beyond the C–C Axial Chirality: Advances in Catalytic Asymmetric Synthesis”, Chem 2022, 8, 1855.
[9] Zhang, F.; Dai, X.; Dai, L.; Zheng, W.; Chan, W.-L.; Tang, X.; Zhang, X.; Lu, Y. “Phosphine-Catalyzed Enantioselective (3+2) Annulation of Vinylcyclopropanes with Imines for the Synthesis of Chiral Pyrrolidines”, Angew. Chem. Int. Ed. 2022, 61, e202203212.
[10] Mei, G.-J.; Wong, J. J.; Zheng, W.; Nangia, A. A.; Houk, K. N.; Lu, Y. “Rational Design and Atroposelective Synthesis of N–N Axially Chiral Compounds”, Chem 2021, 7, 2743.
NUS Webpage
