LI Jun

LI Jun

LI Jun

Chief Principal Investigator

bielj@nus.edu.sg

Educational Qualifications

1981-1985, Department of Chemistry, Sichuan University, B.S.
1990-1992, Department of Macromolecular Science, Osaka University, M.S.
1992-1995, Department of Macromolecular Science, Osaka University, Ph.D.


Work Experience

1985-1987, Sichuan Institute of Chemical Industry Research, China, Research Engineer
1995-1998, Polymer Chemistry Laboratory, the Institute of Physical and Chemical Research (RIKEN), Japan, Special Postdoctoral Researcher
1998-2002, Institute of Materials Research and Engineering (IMRE), Singapore, Research Scientist / Senior Scientist
2002-2007, Department of Biomedical Engineering, National University of Singapore, Assistant Professor
2007-2015, Department of Biomedical Engineering, National University of Singapore, Associate Professor
2015-Present, Department of Biomedical Engineering, National University of Singapore, Professor


Research Interest

Supramolecular self-assembled and nanostructured polymers
Smart biomaterials and hydrogels for drug/gene delivery and nanomedicine applications
Biomass polymers for water treatment, resource recovery, and sustainability applications


Honor & Award

2020, Global Alumni Fellow awarded by Osaka University, Japan
2015, Plenary Speaker, The 4th European Cyclodextrin Conference, Lille, France
2010, Plenary Speaker, The 20th Annual Conference of Australasian Society for Biomaterials and Tissue Engineering (ASBTE 2010), Brisbane, Australia
2009, JSPS (Japan Society for the Promotion of Science) International Fellowship
2008, Invited Lecture of Asia Excellence, The 57th SPSJ (Society of Polymer Science of Japan) Annual Meeting, Japan
1995-1998, RIKEN Special Postdoctoral Fellowship
1995, The Award of Osaka University International Exchange Program in Macromolecular Science
1990-1995, Japanese Government (Monbusho) Graduate Scholarship


Selected Journal Publications
[1] Tang X, Wen Y, Zhang Z, Zhu J, Song X, and Li J*, Rationally designed multifunctional nanoparticles as GSH-responsive anticancer drug delivery systems based on host-guest polymers derived from dextran and β-cyclodextrin, Carbohydrate Polymers, 2023, 320, 121207.

[2] Zhang Z, Zhu J, Song X, Wen Y, Zhu C, and Li J*, Biomass-based single- and double-network hydrogels derived from cellulose microfiber and chitosan for potential application as plant growing substrate, Carbohydrate Polymers, 2023, 319, 121170.

[3] Zheng D, Xu X, Zhu J, Bai B*, Wang Q, Shi W, and Li J*, Humidity capture and solar-driven water collection behaviors of alginate-g-PNIPAm-based hydrogel,Journal of Environmental Chemical Engineering, 2023, 11(1), 109247.

[4] Zhu C, Zhang Z, Wen Y, Song X, Zhu J, Yao Y, and Li J*, Cationic micelles as nanocarriers for enhancing intra-cartilage drug penetration and retention, Journal of Materials Chemistry B, 2023, 11, 1670-1683.

[5] Zhu J, Tan WK, Song X, Zhang Z, Gao Z, Wen Y, Ong CN, Swarup S, and Li J*, Synthesis and Characterization of Okara-Poly(acrylic acid) Superabsorbent Hydrogels for Enhancing Vegetable Growth through Improving Water Holding and Retention Properties of Soils, ACS Food Science & Technology, 2023, 3, 553-561.

[6] Soh WWM, Zhu J, Song X, Jain D, Yim EKF,* and Li J*, Detachment of bovine corneal endothelial cell sheets by cooling-induced surface hydration of poly[(R)-3-hydroxybutyrate]-based thermoresponsive copolymer coating, Journal of Materials Chemistry B, 2022, 10, 8407-8418.

[7] Zhang M, Zhang Z, Song X, Zhu J, Li J*, and Wen Y*, Synthesis and Characterization of Palmitoyl-block-poly(methacryloyloxyethyl phosphorylcholine) Polymer Micelles for Anticancer Drug Delivery, Biomacromolecules, 2022, 23, 4586-4596.

[8] Soh WWM, Teoh RYP, Zhu J, Xun Y, Wee CY, Ding J, Thian ES, and Li J*, Facile Construction of a Two-in-One Injectable Micelleplex-Loaded Thermogel System for Prolonged Delivery of Plasmid DNA,Biomacromolecules, 2022, 23, 3477-3492.

[9] Wen Y, Mensah NN, Song X, Zhu J, Tan WS, Chen X, Li J*, Hydrogel with supramolecular surface functionalization for cancer cell capture and multicellular spheroid growth and release, Chemical Communications, 2022, 58, 681-684.

[10] Li H, Peng E, Zhao F, Li J*, Xue JM*, Supramolecular Surface Functionalization of Iron Oxide Nanoparticles with α-Cyclodextrin-Based Cationic Star Polymer for Magnetically Enhanced Gene Delivery, Pharmaceutics, 2021, 13(11), 1884.

[11] Zhang Z, Wen Y, Song X, Zhu J, Li J*, Nonviral DNA Delivery System with Supramolecular PEGylation Formed by Host-Guest Pseudo-Block Copolymers, ACS Applied Bio Materials, 2021, 4, 5057-5070.

[12] Wen Y, Bai H, Zhu J, Song X, Tang G, Li J*, A supramolecular platform for controlling and optimizing molecular architectures of siRNA targeted delivery vehicles, Science Advances, 2020, 6, eabc2148.

[13] Zhu J, Tan WK, Song X, Gao Z, Wen Y, Ong CN, Loh CS, Swarup S, Li J*, Converting okara to superabsorbent hydrogels as soil supplements for enhancing the growth of choy sum (brassica sp.) under water-limited conditions, ACS Sustainable Chemistry & Engineering, 2020, 8(25), 9425-9433.

[14] Zhu J, Song X, Tan WK, Wen Y, Gao Z, Ong CN, Loh CS, Swarup S, Li J*, Chemical modification of biomass okara using poly(acrylic acid) through free radical graft polymerization,Journal of Agricultural and Food Chemistry, 2020, 68(46), 13241-13246.

[15] Song X, Zhang Z, Zhu J, Wen Y, Zhao F, Lei L, Phan-Thien N, Khoo BC, Li J*, Thermoresponsive Hydrogel Induced by Dual Supramolecular Assemblies and Its Controlled Release Property for Enhanced Anticancer Drug Delivery, Biomacromolecules,2020, 21, 1516-1527.

[16] Ooi YJ, Wen Y, Zhu JL, Song X, Li J*, Surface charge switchable polymer/DNA nanoparticles responsive to tumor extracellular pH for tumor-triggered enhanced gene delivery, Biomacromolecules, 2020, 21(3),1136−1148.

[17] Liu M, Wen YT, Song X, Zhu JL, Li J*, A smart thermoresponsive adsorption system for efficient copper ion removal based on alginate-g-poly(N-isopropylacrylamide) graft copolymer, Carbohydrate Polymers, 2019, 219, 280-289.

[18] Zhu JL, Yu SWK, Chow PKH, Tong YW, Li J*, Controlling injectability and in vivo stability of thermogelling copolymers for delivery of yttrium-90 through intra-tumoral injection for potential brachytherapy, Biomaterials, 2018, 180, 163-172.

[19] Wen Y & Li J*, Ultrastable micelles boost chemotherapy,Nature Biomedical Engineering, 2018, 2, 273–274. , Colloids and Surfaces B: Biointerfaces, 2018, 169, 214-221.


NUS Webpage

https://cde.nus.edu.sg/bme/staff/dr-lijun/


Other Investigators

CHEN Nanguang
CHEN Nanguang

Senior Principal Investigator

biecng@nus.edu.sg
GUO Yongxin
GUO Yongxin

Chief Principal Investigator

yongxin.guo@nus.edu.sg
HUANG Dejian
HUANG Dejian

Chief Principal Investigator

fsthdj@nus.edu.sg
LI Dan
LI Dan

Principal Investigator

dan.li@nus.edu.sg
LIM CHWEE TECK
LIM CHWEE TECK

Chief Principal Investigator

ctlim@nus.edu.sg
LEE Chengkuo
LEE Chengkuo

Senior Principal Investigator

elelc@nus.edu.sg
LIU Shaoquan
LIU Shaoquan

Senior Principal Investigator

fstLsq@nus.edu.sg
QIU Anqi
QIU Anqi

Senior Principal Investigator

bieqa@nus.edu.sg
YU Haoyong
YU Haoyong

Senior Principal Investigator

bieyhy@nus.edu.sg
ZHOU Weibiao
ZHOU Weibiao

Chief Principal Investigator

weibiao@nus.edu.sg
ZHOU Zhiying
ZHOU Zhiying

Senior Principal Investigator

elezzy@nus.edu.sg