LIM CHWEE TECK

LIM CHWEE TECK

LIM CHWEE TECK

Chief Principal Investigator

ctlim@nus.edu.sg

Educational Qualifications

1990 B.Eng (First Class Honours), National University of Singapore, Singapore
1996 PhD, University of Cambridge, UK


Work Experience

2008 – current  Principal Investigator, Mechanobiology Institute, NUS

2017 – current  NUSS Professor, Department of Biomedical Engineering, NUS

2018 – current  Director, Institute for Health Innovation & Technology

2019 – current  Founding Director, Singapore Health Technologies Consortium

2021 – current Principal Investigator, Institute for Functional Intelligent Materials, NUS


Research Interest

Human disease Mechanobiology, Microfluidic biomedical technology, Wearable technology


Selected scientific awards & Honors (Over 100)

1.  Elected Fellow, Institution of Engineers Singapore 2023

2.  Nature Lifetime Achievement Award for Mentoring in Science 2022

3.  IES Prestigious Engineering Achievement Award 2022

4.  Elected Fellow, International Union for Physical & Engineering Sciences in Medicine, 2022

5.  Asia’s Most Influential Scientist, Fortune Times, 2021

6.  Highly Cited Researcher 2018, 2019, 2021

7.  IES Prestigious Engineering Achievement Award 2021, 2016, 2010

8.  Elected Fellow, ASEAN Academy of Engineering and Technology 2021

9.  Elected Fellow, US National Academy of Inventors 2020

10. Elected Fellow, Singapore National Academy of Science 2020

11. IP Champion, IPOS-WIPO IP Awards 2019

12. Human Frontier Science Program Research Grant Award 2012, 2018

13. Elected Fellow, ASEAN Outstanding Engineering Achievement Award 2016

14. Asian Scientist 100, 2016

15. Vladimir K. Zworykin Award, 2015

16. Elected Fellow, International Academy of Medical and Biological Engineering 2016

17. Elected Fellow, American Institute for Medical and Biological Engineering 2016

18. Elected Fellow, Academy of Engineering Singapore 2016

19. Gold, Wall Street Journal Asian Innovation Awards 2012

20. Credit Suisse Technopreneur of the Year Award 2012

21. President’s Technology Award 2011


Relevant Publications 

Authored >470 peer-reviewed journal papers; > 450 plenary/keynote/invited talks; 31 book chapters; over 60 filed and granted patents; (Citation count > 58,800, h-index = 122 (Google Scholar Citations)).

1.    Chen, S W, Q Zheng, Y Niu, J C Yeo, Y C Liu, J M Qi, S C Fan, X Y Liu, J Y Lee, C T Lim, Wearable flexible microfluidic sensing technologies, Nature Reviews Bioengineering, 2023.

2.    Qi, J, F Gao, G Sun, J C Yeo, C T Lim, HaptGlove—Untethered Pneumatic Glove for Multimode Haptic Feedback in Reality–Virtuality Continuum, Advanced Science, 2301044, 2023.

3.    Saw, T B, et al., Transepithelial potential difference governs epithelial fate by electromechanics, Nature Physics, 18, 9, 1122-1128, 2022.

4.    Gaston, C, et al., EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization, Nature Communications, 12, 1, 1-22, 2021.

5.    Gao, Y J, et al., A wearable multifunctional immunosensor for the monitoring of chronic wounds, Science Advances, 2021.

6.    Phuong Le, A, et al., Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion, Nature Communications, 12, 397, 2021.

7.    Yu, G, et al., Flexible Hybrid Sensors for Health Monitoring: Materials and Mechanisms to Render Wearability, Advanced Materials, 32, 15, 1902133, 2020.

8.    Jain, S, et al., Emergence of single cell mechanical behavior and polarity within epithelial monolayers drives collective cell migration, Nature Physics, 16, 802–809, 2020.

9.    Sun*, A X, et al., Potassium Channel Dysfunction in Human Neuronal Models of Angelman Syndrome, Science, 366, 1486–1492, 2019.

10. Xi, W, et al., Material Approaches to Active Tissue Mechanics, Nature Reviews Materials, 4, 23–44, 2019.

11. Ding, X, et al., Defect Engineered Bioactive Transition Metals Dichalcogenides Quantum Dots, Nature Communications, 10, 41, 2019.

12. Lim, S B, et al., Addressing Cellular Heterogeneity in Tumor and Circulation for Refined Prognostication, PNAS, 116, 17957–17962, 2019.

13. Saw, T B, et al., Biological Tissues as Active Nematic Liquid Crystals, Advanced Materials, 30, 1802579, 2018.

14. Saw, T B, et al., Topological Defects in Epithelia Govern Cell Death and Extrusion, Nature, 544, 212–216, 2017.

15. Xi, W, et al., Emergent Patterns of Collective Cell Migration under Tubular Confinement, Nature Communications, 8, 1517, 2017.


Selected patents filed or granted (over 60):

1.   Lim. C T, Q M P Nguyen, Y L A Li, M Wang, N Venugopal Menon, M R G Xiong, A A Saleem Bhagat, J C Teoh, A Portable Integrated Modular System For Microfluidic Based Nucleic Acid Testing, DNA Assembly and Transformation, SG Non-Provisional Application No. 10202005023R filed on 28 May 2020.

2.    W Xi, C T Lim, F Kong, X Gong, Versatile, Biocompatible Elastomeric Microtubes, European Patent Application No. 3422999 on 9 Jan 2019.

3.    B L Khoo, C T Lim, G Grenci, Cell Culture, European Patent Application No. 3448986 filed on 4 Dec 2018.

4.    Kenry, J C Yeo, C T Lim, A Resistive Microfluidic Pressure Sensor, US patent pub no. 2018/006700 published on 8 Mar 2018.

5.    J C Yeo, W Xi, L Yu, C T Lim, Microtube Sensor for Physiological Monitoring, US Patent Application No. 62/465,002 filed on 28 Feb 2017.

6.    Kenry, J C Yeo, C T Lim, Highly Wearable Flexible Liquid Graphene Oxide-Based Microfluidic Resistive Pressure Sensor, US Provisional Application Serial No. 62/137,391 filed on 24 March, 2015.


NUS Webpage

https://cde.nus.edu.sg/bme/staff/dr-limchweeteck/ 


Other Investigators

CHEN Nanguang
CHEN Nanguang

Senior Principal Investigator

biecng@nus.edu.sg
GUO Yongxin
GUO Yongxin

Chief Principal Investigator

yongxin.guo@nus.edu.sg
HUANG Dejian
HUANG Dejian

Chief Principal Investigator

fsthdj@nus.edu.sg
LEE Chengkuo
LEE Chengkuo

Senior Principal Investigator

elelc@nus.edu.sg
LI Dan
LI Dan

Principal Investigator

dan.li@nus.edu.sg
LI Jun
LI Jun

Chief Principal Investigator

bielj@nus.edu.sg
LIU Shaoquan
LIU Shaoquan

Senior Principal Investigator

fstLsq@nus.edu.sg
QIU Anqi
QIU Anqi

Senior Principal Investigator

bieqa@nus.edu.sg
YU Haoyong
YU Haoyong

Senior Principal Investigator

bieyhy@nus.edu.sg
ZHOU Weibiao
ZHOU Weibiao

Chief Principal Investigator

weibiao@nus.edu.sg
ZHOU Zhiying
ZHOU Zhiying

Senior Principal Investigator

elezzy@nus.edu.sg